@article{Gunn_Crawshaw_Brookes_2020, title={Insufficient evidence intraperitoneal fluid is equivalent or superior to intravenous fluid therapy in dehydrated calves}, volume={5}, url={https://veterinaryevidence.org/index.php/ve/article/view/218}, DOI={10.18849/ve.v5i1.218}, abstractNote={<p><strong>PICO question</strong></p> <p>In calves <14 days old which are moderately to severely dehydrated (5–9%) or acidaemic (base excess -5 to  -15 mM), does intraperitoneal fluid therapy result in comparable or superior clinical improvement when compared to intravenous fluid therapy?</p> <p> </p> <p><strong>Clinical bottom line</strong></p> <p><strong>Category of research question</strong></p> <p>Treatment</p> <p><strong>The number and type of study designs reviewed</strong></p> <p>Two papers were critically reviewed (one randomised clinical trial and one case series)</p> <p><strong>Strength of evidence</strong></p> <p>Weak evidence relevant to the topic question</p> <p><strong>Outcomes reported</strong></p> <p>Statistically significant differences were not found between treatment groups (administration of intravenous fluids [n = 27] or intra-peritoneal fluids [n = 28]) in the clinical trial, and findings relevant to the topic question were not reported in the case series of 18 calves</p> <p><strong>Conclusion</strong></p> <p>These studies provide insufficient evidence that intraperitoneal (IP) fluid is comparable to, or  provides superior clinical improvement, when compared to intravenous (IV) fluid therapy in moderately to severely dehydrated (5–9 %) or acidaemic calves (base excess -5 to -15 mM) aged < 14 days of age</p> <p> </p> <p><strong><a href="http://www.ebvmlearning.org/apply/" target="_blank" rel="noopener">How to apply this evidence in practice</a></strong></p> <p>The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.</p> <p>Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.</p> <p> </p> <p><img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access"> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/pr-icon.jpg" alt="Peer Reviewed"></p>}, number={1}, journal={Veterinary Evidence}, author={Gunn, Allan John and Crawshaw, Timothy and Brookes, Victoria}, year={2020}, month={Feb.} }