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Evidence Supporting Intralesional Stem Cell Therapy to Improve Equine Flexor Tendon Healing

Sushmitha Durgam, Matthew Stewart

Published:  03/01/2017    in:  Knowledge Summaries
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Abstract

Clinical bottom line

Current experimental evidence suggests that intralesional stem cell administration improves the histological characteristics and matrix organisation of healing equine superficial digital flexor tendons (SDFT); however, the clinical relevance of these findings are not clear. Current case-based evidence suggests that cell-based therapies improve the quality of tendon healing and reduce the recurrence rates of SDFT injuries but the lack of any randomised, controlled prospective studies with function-based outcomes is still concerning, given the widespread advocacy for and use of ‘stem cell’ therapies for the treatment of equine tendon injuries.

 

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References

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