In horses with arthritis, does the treatment with intra-articular antimicrobials concurrently with intra-articular corticosteroids reduce the risk of sepsis compared to intra-articular corticosteroids alone?
Clinical bottom line
The three studies identified did not demonstrate a reduction of risk when antimicrobials were used. However, the strength of evidence provided by the studies was weak. The power of the studies to detect an effect of antimicrobials was low due to the small number of sepsis cases recorded. Further studies are therefore required to draw conclusions.